Pesquisa sobre:
RNA-INDUCED SILENCING COMPLEX
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
RNA-Induced Silencing Complex
Descritor
Espanhol
:
Complejo Silenciador Inducido por ARN
Descritor
Português
:
Complexo de Inativação Induzido por RNA
Categoria:
D08.811.277.352.355.350.810
D08.811.277.352.700.350.810
D12.776.157.725.500.906
D12.776.664.962.500.906
Definição
Inglês
:
A multicomponent, ribonucleoprotein complex comprised of one of the
family
of
ARGONAUTE PROTEINS
and the "guide strand" of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating
gene expression
are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA).
Relacionados
Inglês
:
RNA Interference
RNA, Small Interfering
Nota Histórica
Inglês
:
2003; use RNA-INDUCED SILENCING COMPLEX (NM) 2001-2002
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
37323
Identificador Único:
D034743
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
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